Woman Returns From Vacation With Brain Worm That Left Her in Agonizing Pain—Doctors Were Stumped

By Searchpanda - February 24, 2025

After returning from a three-week adventure across Hawaii, Japan, and Thailand, a 30-year-old woman from New England began experiencing a bizarre and frightening symptom: a burning sensation that started in her feet and soon spread to her legs. Initially dismissed as jet lag-induced fatigue, her condition rapidly deteriorated, prompting multiple visits to the emergency room.
Despite her worsening symptoms, which eventually included headaches, confusion, and sensitivity in her limbs, initial medical tests failed to pinpoint the cause of her distress. It was not until her condition escalated, impairing her cognitive functions and physical health, that further investigations were conducted.

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Diagnosis: Eosinophilic Meningitis Due to Rat Lungworm

The mystery was finally solved during a subsequent ER visit where an elevated white blood cell count hinted at an inflammatory process. Detailed tests confirmed the presence of eosinophilic meningitis, an inflammation of the brain and spinal cord, often triggered by parasitic infections. The culprit? Angiostrongylus cantonensis, commonly known as rat lungworm, a parasite endemic to the Pacific and Southeast Asia regions she had visited.
Symptoms of this infection can be severe, ranging from headaches and vomiting to neurological issues such as confusion, stiff neck, and, in extreme cases, seizures and vision problems. The New England Journal of Medicine, which published the case study, highlights the critical nature of this condition, underscoring the importance of prompt and accurate diagnosis.

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Prevention and Protection: Tips for Travelers

The Centers for Disease Control and Prevention (CDC) advises travelers to exercise caution with food consumption in regions known for Angiostrongylus cantonensis. Avoiding raw or undercooked snails, slugs, frogs, shrimp, and prawns is essential. For those who come into contact with these animals, whether in the kitchen or garden, wearing gloves and thorough washing are recommended to prevent infection.
Moreover, consuming uncooked vegetables in areas where the parasite is prevalent should be avoided, as these can also be carriers of the dangerous larvae. Such preventive measures are crucial in safeguarding against this and other similar infections, which can turn a dream vacation into a nightmare.

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This incident serves as a stark reminder of the unexpected health risks associated with international travel. Awareness and proper preventive measures can significantly reduce the risk of contracting such dangerous infections. Travelers are urged to educate themselves about the potential health risks in their destinations and to adhere strictly to recommended safety guidelines to enjoy a safe and healthy journey.